Our approach

People-Driven Therapeutics

There is a pressing need for new ways to treat disease, but drug development has become increasingly difficult due to high costs and failure rates. Human genetics has the power to transform drug development, because it uses human diversity to identify the basis of disease and resistance to it.

woman in laboratory

Genetic Studies

By studying the genomes of people with exceptional health-related traits, genetic studies have inspired new therapies to lower cholesterol and treat osteoporosis.


Global Partnership Network

Genetic studies are only as informative as the people in them. Variant Bio combines anthropology, epidemiology, and genetics to identify relevant groups to partner with. We focus on exceptional health-related traits and populations with rare genetic variants that rise to high frequency.


Technology Powered

Using innovative low- and high-pass whole-genome sequencing alongside custom algorithms we can reduce costs without sacrificing data quality. Our approach is better suited to identify novel and population-specific genetic variants than genotyping arrays, and captures much more of the genome than exome-sequencing.


From Genomes to Targets

We look for associations between genetic variants and traits that have global medical relevance using statistical genetics. By focusing on populations with exceptional health-related traits, we can sequence fewer genomes to make novel discoveries.


Improving Global Health

We focus on therapeutic areas with global markets and unmet need including kidney, liver, metabolic, and inflammatory diseases.

Variant Bio was built from the ground up to leverage the power of genetics for drug development.

Our approach is powered by modern technology and brings communities, academia, healthcare providers, and the pharmaceutical industry under one roof to improve global health.